![]() The difference between MwA and MwoA remained significant in the overall group after the adjustment for vascular comorbidities, (least-squares mean difference, 0.7% 95% CI, 0.4-0.9 P <.001), 18 to <35 (LSMD, 0.4% 95% CI, 0.1-0.7 P=. For the comparison between MwA and MwoA, they were conducted in an overall group (including men and women of all ages), women only, and men only in each age range (18 to <35, 35 to <55, 55 to <75, ≥75 years), and adjusted for age, sex, and six common vascular comorbidities that were known to increase risk for AFib. The ECG with the highest AFib prediction model output was used as the index ECG for each patient. The Mayo Clinic identified adult patients with an MwA or MwoA diagnosis within the past 20 years while patients with an ECG-confirmed diagnosis of AFib were excluded. This included both women and men of all ages in the study and the use of a single ECG as point-of-care test. The research was performed through a cross-sectional study which included the application of a novel AI-ECG algorithm from the Mayo Clinic Cardiology team, to evaluate the risk of undetected paroxysmal AFib in a large group of adult patients with migraine. 5.6% mean difference, 1.7% P <.001).Ĭhiang et al noted that, “Few studies have specifically investigated the risk of in patients with migraine in different age and sex groups.” Their study overall demonstrated the power that modern computing technology has in analyzing big data to help clarify the association between two conditions unrelated to each other, migraine and AFib. 1 The MwA group, compared with MwoA, had a significantly higher AFib prediction model output (mean, 7.3% vs. In the final analysis, 40,002 patients (17,840 with MwA, 22,162 with MwoA) were included with the mean age at the index ECG of 48.2 years (SD, 16.0) years for MwA and 45.9 years (SD, 15.0) for MwoA (P <.001). Chiang et al demonstrated in their study, “that patients with MwA have a significantly higher AFib prediction model output, implying a higher probability of concurrent paroxysmal or impending AFib, compared to MwoA in both women and men.” 1Ĭhia-Chun Chiang, MD, assistant professor of neurology, Mayo Clinic, and colleagues conducted a study that compared the AI-ECG AFib prediction model output in patients with MwA and migraine without aura (MwoA). The results of a study utilizing an artificial intelligence (AI)-enabled electrocardiogram (ECG) prediction model suggest that migraine with aura (MwA) may be an independent risk factor for atrial fibrillation (AFib), particularly among those younger than 55 years of age.
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